Physiology of Spinal Perfusion
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Abstract
Introduction: Over the past decades the interest in the study of the physiology of perfusion at the level of the spinal cord has increased. Many treatments in patients with spinal cord injury have been based on the parallelism of the vascular dynamics between the brain and the spinal. Knowing about these aspects and methods related to their monitoring practice is favorable for a proper intervention of the patient with spinal cord injury. Objective: To do a scientific literature review on the most important aspects involved in spinal cord perfusion, autoregulatory mechanisms and their clinical applications in the study of spinal cord physiology. Methods: Using the keywords, a non-systematic review on the OVID, Medline/PubMed and Science Direct databases, was performed. Results and Conclusion: The role of autoregulation is vital in maintaining the integrity of the spinal cord, an adequate control of it as well as other chemical and metabolic factors are important in the control of medullary blood flow and minimizes the risk of secondary spinal cord injury. The autoregulation curves for the brain and spinal cord are virtually identical, within a range of 60-150 mmHg.
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Spinal cord, perfusion pressure, autoregulation, medullary blood flow






